| 0014 August 20 | Death | Augustus Caesar | First Roman Emperor. |
| 0040 June 13 | Death | The Virgin Mary | Possible. |
| 0044 July 25 | Death | Saint James the Greater. | |
| 0067 August 1 | Death | Martyrdom of Saint Peter. | |
| 0068 June 9 | Death | Claudius Nero | Roman Emperor (54-68). |
| 0222 October 14 | Death | Saint Callixtus I | Pope (222) |
| 0238 May 10 | Death | Gaius Julius Verus Maximinus, "The Thracian" | Roman Emperor murdered. |
| 0257 August 2 | Death | Saint Stephen I | Pope |
| 0258 August 6 | Death | Saint Sixtus II | Pope |
| 0258 September 16 | Death | Saint Cyprian | |
| 0259 April 30 | Death | Sts Marian and James | |
| 0298 October 30 | Death | Saint Marcellus the Centurion. | |
| 0303 April 23 | Death | George, Knight of Cappadoci (?) | Patron Saint of England was beheaded. |
| 0303 July 15 | Death | Saint Felix of Thibiuca | |
| 0303 July 8 | Death | Saint Procopius | |
| 0304 April 3 | Death | St. Pancras of Taormina | |
| 0304 April 5 | Death | Saints Agape, Chiona and Irene | |
| 0304 October 22 | Death | Saint Philip of Heraclea | |
| 0304 October 23 | Death | Saint Severus | |
| 0311 May 5 | Death | Emporor Gaius VM Galerius | of Rome, dies at about 50. |
| 0311 November 26 | Death | St Peter of Alexandria | Martyred on this day. |
| 0328 May 4 | Death | St Helena | for the Cross of Christ at Jerusalem |
| 0336 October 7 | Death | Saint Mark | Pope. |
| 0337 May 22 | Death | Constantine the Great | Emperor of Rome |
| 0338 July 15 | Death | Saint James of Nisibus | |
| 0347 May 14 | Death | Pachomius | Egyptian monastery founder. |
| 0352 April 12 | Death | Julius I | Pope |
| 0363 July 26 | Death | Julian the Apostate | |
| 0366 September 24 | Death | Pope Liberius | |
| 0372 April 12 | Death | St. Sabas the Goth | |
| 0373 June 18 | Death | Saint Ephraem | |
| 0379 July 19 | Death | Saint Macrina | the Younger. |
| 0392 May 15 | Death | Valentinius II | Emperor of Rome (375-392) |
| 0397 April 5 | Death | St. Ambrose | |
| 0408 August 23 | Death | Stilicho dies | |
| 0410 August 30 | Death | Saint Pammachius | |
| 0420 September 30 | Death | Saint Jerome | |
| 0422 September 4 | Death | Saint Boniface | Pope |
| 0430 August 28 | Death | Saint Augustine of Hippo | |
| 0440 August 19 | Death | Pope Sixtus III | |
| 0448 July 31 | Death | Saint Germanus | of Auxerre. |
| 0453 September 10 | Death | Saint Pulcheria | Empress of Byzantium |
| 0455 May 31 | Death | Petronius Maximus | Emperor of Rome was Lynched. |
| 0459 July 24 | Death | Saint Simon Stylites. | |
| 0461 March 17 | Death | St Patrick | Patron Saint of ireland dies in Saul according to the ledgends. |
| 61 September | Death | Bodacia | Queen in England |
